Eicosapentaenoic Acid (EPA) in Arteriosclerosis. I.

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Clinical and epidemiological study of eicosapentaenoic acid (EPA) in Japan.

Between 1978 and 1980, we investigated and compared the dietary intake of fish meat, platelet function, rheological properties of blood and mortality rate due to thrombotic cardiovascular diseases between the residents of fishing and farming villages. Notable finding is that the dietary intake of EPA in the residents of fishing village was nearly 3 times (2.5 g/day) higher than that (0.9g/day) ...

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Eicosapentaenoic acid (EPA) reduces cardiovascular events: relationship with the EPA/arachidonic acid ratio.

The clinical efficacy of fish oil and high-purity eicosapentaenoic acid ethyl ester (hp-EPA-E) for treating cardiovascular disease (CVD) has been reported. Fish oil contains saturated and monounsaturated fatty acids that have pharmacological effects opposite to those of ω3 fatty acids (ω3). Moreover, ω3, such as EPA and docosahexaenoic acid (DHA), do not necessarily have the same metabolic and ...

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Dietary effect of eicosapentaenoic acid (EPA) containing soyphospholipid.

In this study, we evaluated on a comparative basis the dietary effect between eicosapentaenoic acid (C20:5, EPA)- containing soyphospholipid and soyphospholipid without EPA when added at 5% or 10% level by weight in soybean oil as the dietary oil on the proportions of lipid components in serum of rats. Rats were taken in five groups. One group was fed 20% soybean oil. Two groups received soybea...

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Dietary intake of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in children - a workshop report.

There is controversy whether children should have a dietary supply of preformed long-chain polyunsaturated n-3 fatty acids EPA and DHA. The aims of the workshop were to review evidence for a possible benefit of a preformed EPA and/or DHA supply, of data required to set desirable intakes for children aged 2-12 years, and of research priorities. The authors concluded that EPA and DHA intakes per ...

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Relationship between arteriosclerosis obliterans and the ratio of serum eicosapentaenoic acid to arachidonic acid.

PURPOSE A low ratio of serum eicosapentaenoic acid to arachidonic acid (EPA/AA) has been associated with coronary artery disease. We retrospectively examined serum concentrations of polyunsaturated fatty acids in patients with arteriosclerosis obliterans (ASO) and in non-atherosclerotic patients. METHODS From April 2011 to March 2012, serum EPA/AA was retrospectively examined in 33 consecutiv...

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ژورنال

عنوان ژورنال: The Journal of Japan Atherosclerosis Society

سال: 1983

ISSN: 0386-2682,2185-8284

DOI: 10.5551/jat1973.10.6_1089